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Oxycodone should be used with extreme caution in patients with significant chronic obstructive pulmonary disease and in patients having a substantially decreased respiratory reserve, hypoxia, hypercapnia, or preexisting respiratory depression.

At intoxicating doses, alcohol can decrease heart rate, lower blood pressure and respiration rate, and result in decreased reflex responses and slower reaction times.

Darvocet produces psychological and physical dependence like other narcotics, and treatment for Darvocet addiction is much the same.

Morphine is a narcotic analgesic. Morphine was first isolated from opium in 1805 by a German pharmacist, Wilhelm Sert�rner.

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ECSTASY DEPLETES BRAIN OF MOOD CHEMICAL




Using the recreational drug Ecstasy reduces the amount of a brain chemical that controls mood, pain perception, sleep, appetite and emotions, researchers say. The chemical is called serotonin.
In the study, published in the journal Neurology, the scientists report how they compared the brain of a 26-year-old man who died of a drug overdose to those of 11 individuals who did not abuse drugs. The man had used Ecstasy for nine years and cocaine and heroin in the final months of his life. "The levels of serotonin and another chemical associated with serotonin were 50 to 80 percent lower in the brain of the Ecstasy user," said study author Stephen Kish of the Centre for Addiction and Mental Health in Toronto, Canada.
"This is the first study to show that this drug can deplete the level of serotonin in humans." Ecstasy, known chemically as methylenedioxymethamphetamine, or MDMA, is structurally related to the hallucinogen mescaline and the stimulant amphetamine. MDMA causes& neurons, or nerve cells, to release serotonin.

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